Singapore became an independent nation on 9th August 1965 with a population of 2 million, per capita GDP of US$526 and a territory of 1400 square kilometre. The priority of the Government was the creation of jobs, defending the country, providing education for the young and medical services and homes for the population. Centralized planning at the national level was necessary in the early years. The process of centralized planning and decentralized execution evolved over time. The need to create jobs remain a major preoccupation of the Government. The balance between investment in economic development, social development and national security is carefully managed to achieve optimization at the national level. Examples from the strategic systems of creation of usable space, supply of portable water and the future economic system based on research, innovation and enterprise will be used to illustrate the Systems Approach taken in planning and development of large scale systems.